H3N2 mutation in last year's flu vaccine responsible for lowered efficacy

65-year-old Nebraskan dies from the flu, DHHS advises others to get vaccinated
Protect yourself from the flu
Author

08 November, 2017

Researchers around the world, including at the University of Rochester Medical Center (URMC), are pursuing a "universal" flu vaccine, one that would protect against most or all seasonal and pandemic strains of the flu virus. Most flu vaccine proteins are purified from a virus grown in chicken eggs, although a small fraction of flu vaccine proteins are produced in systems that do not involve eggs. "A universal flu vaccine based on the stalk would be more broadly protective than the ones we use now, but this information should be taken into account as we move forward with research and development".

Conventional vaccines are reportedly less than 60% effective-and that's only when they're matched with the now circulating strain.

The Public Health Agency of Canada estimated that the flu causes about 3,500 deaths each year in Canada alone.

A nurse vaccinates U.S. President Barack Obama against the H1N1 flu at the White House in 2009.

The vaccine for the season 2017-2018 is similar to that of 2016, which bodes for a season "difficult if it is again dominated by the H3N2 viruses", said Scott Hensley, a professor at the faculty of medicine Perelman university of Pennsylvania and the lead author of this work, recommending however the vaccination. For example they may have got a food vaccine and got sick anyway.

New York City truck attack: Federal Bureau of Investigation speaking with 2nd Uzbek man
The FBI is looking for a second suspect who may have been involved in the terror attack in lower Manhattan on Tuesday. New York City attack suspect Sayfullo Habibullaevic Saipov shown in court Wed., Nov. 1, 2017.


Rafael Nadal secures year-end No 1 spot after remarkable 2017 season
Nadal, who is tied for a record 30 Masters titles with Djokovic, has never won the tournament in Paris. Nadal celebrates his victory and said: "I never dreamed of being world No.1 at the end of the season".


Most Houston Texans Take a Knee After Owner's 'Inmates' Comment
About ten players stood with their hands over their hearts, according to The Houston Chronicle . Several players publicly came out against the owner's comments, including veteran Duane Brown.


The goal is to combine the desired HA and NA antigens from the target strain (flu strain 1) with genes from a harmless strain that grows well in an egg (flu strain 2).

"Some of the hospitals in York Region have developed their own in-house campaign and have accessed our staff to support them in providing infection prevention and control education on the importance of influenza immunizations", the email said.

The current strain of H3N2 emerged during the 2014-15 flue season and remains prevalent today. Interestingly, the sugar-adorned viruses are not found in vaccines made using other methods.

The vaccines effectiveness in mice is an encouraging sign, but a lot more testing needs to be done before it could become commercially available. "Our data suggest that we should invest in new technologies that allow us to ramp up production of influenza vaccines that are not reliant on eggs".


More news


  • Gurriel issued five-game ban by Manfred, but not in World Series

    Gurriel issued five-game ban by Manfred, but not in World Series

    With his impending suspension deferred to 2018, Gurriel will stick in his usual spot in the order against the Dodgers for Game 4. I've never had anything against Darvish. "I did not mean it to be offensive at any point", Gurriel told reporters .
    Harry Kane Has Just Been Ruled Out Of Manchester United Clash

    Harry Kane Has Just Been Ruled Out Of Manchester United Clash

    One player who will be available for Mourinho on Saturday is Nemanja Matic. We have Fernando [Llorente], Son [Heung-min], we have options.
    O'Reilly: I'm 'mad at God' over allegations of sexual harassment

    O'Reilly: I'm 'mad at God' over allegations of sexual harassment

    It meant a lot to me + Doug. "The coroner has in fact indicated to us that that they believe it was an accident". Is it your opinion or do you know it to be true? Bill - Thank you for being the calm in the sea .
  • Rand Paul tackled by neighbor over

    Rand Paul tackled by neighbor over "trivial" dispute

    The Republican "was blindsided and the victim of an assault" on Friday, a spokeswoman for him was quoted by U.S. media as saying. In the arrest warrant , Paul said he was mowing his lawn when "his neighbor came onto his property and tackled him from behind".
    Puerto Rico Governor Calls For Termination Of Whitefish Contract

    Puerto Rico Governor Calls For Termination Of Whitefish Contract

    The contract states that "Prepa hereby represents and warrants that Fema has reviewed and approved of this Contract". And that the Puerto Rican government "waives any claim against contractor related to delayed completion of work ".

    Here's Why Everyone Thinks Kanye West & Taylor Swift Beef's Far From Over

    One user questioned the fans' hand placements October 15, writing, "why are your hands on her stomach??? is she pregnant or what". Us Weekly reports that, this time around, Taylor's music is "her most experimental work yet in terms of sound".
  • Mueller has enough evidence to bring charges in Flynn investigation

    Mueller has enough evidence to bring charges in Flynn investigation

    Several sources told NBC News that the younger Flynn could be indicted at the same time, or separately from his father. Flynn's son had reportedly worked closely with his father at his lobbying firm, the Flynn Intel Group.
    George HW Bush on Trump: 'I Don't Like Him'

    George HW Bush on Trump: 'I Don't Like Him'

    The most critical comments about Trump came from the elder Bush, now 93, who told Updegrove in May 2016, "I don't like him". Bush thought he would not last, and he was surprised by the real estate developer's success at capturing the nomination.
    First Bharatmala projects to start by 2018: Gadkari

    First Bharatmala projects to start by 2018: Gadkari

    The government also plans to improve the speed of traffic movement on key corridors by providing uniform four-lane roads. The government on Tuesday approved a package of Rs 6.9 lakh crore to build approximately 83,000 km of highways by 2022.
  • Trump Announces Major Company Is Moving to the US

    Trump Announces Major Company Is Moving to the US

    The move to reincorporate in DE is largely symbolic for Broadcom, which maintains about half of its global workforce in the U.S. Broadcom Chief Executive Officer Tan Hock joined Trump on Thursday (Nov 2) in the Oval Office for the announcement.
    Citizen Android: Saudi Arabia becomes first country to grant citizenship to robot

    Citizen Android: Saudi Arabia becomes first country to grant citizenship to robot

    The country has become the first to grant a robot citizenship , an event mentioned during his interview with Sophia . If Sophia were a robot , her choice of dress would have offended Saudis religious hardliners.
    Weinstein assaulted me in child's room, says production assistant Mimi Haleyi

    Weinstein assaulted me in child's room, says production assistant Mimi Haleyi

    When Weinstein returned from Paris, he invited her to his residence, which had children's drawings on display, she said. Once back in Los Angeles, Malthe said Weinstein called her to check in about a role she was training and preparing for.